STUDIES ON THE METABOLISM OF α-LIPOIC ACID IN CHILDHOOD

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چکیده

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Spectroscopic Studies of R(+)-α-Lipoic Acid—Cyclodextrin Complexes

α-Lipoic acid (ALA) has a chiral center at the C6 position, and exists as two enantiomers, R(+)-ALA (RALA) and S(-)-ALA (SALA). RALA is naturally occurring, and is a cofactor for mitochondrial enzymes, therefore playing a major role in energy metabolism. However, RALA cannot be used for pharmaceuticals or nutraceuticals because it readily polymerizes via a 1,2-dithiolane ring-opening when expos...

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ژورنال

عنوان ژورنال: THE JOURNAL OF VITAMINOLOGY

سال: 1965

ISSN: 0022-5398

DOI: 10.5925/jnsv1954.11.54